Publications

Synthesis and biological activity of scyllatoxin-based BH3 domain mimetics containing two disulfide linkages. D. Arachchige & J. M. Holub. Protein J. 2018, 37, 428-443. PubMed. PDF.
Inhibiting phosphorylation of tau proteins using peptide-based R1-domain mimetics. N. Alqaeisoom, C. Qian, D. Arachchige, R. A. Colvin & J. M. Holub. Int. J. Pept. Res. Ther., 2018, 25, 447-463. PubMed. PDF.
Intracellular zinc increase affects phosphorylation state and subcellular localization of protein kinase C delta. K. G. Slepchenko, J. M. Holub & Y. V. Li. Cell. Signal., 2018, 44, 148-157. PubMed. PDF.
Small scaffolds, big potential: Developing miniature proteins as therapeutic agents. J. M. Holub. Drug Dev. Res., 2017, 78, 268-282. PubMed. PDF.
Role of single disulfide linkages in the folding and activity of scyllatoxin-based BH3 domain mimetics. D. Arachchige, M. M. Harris, Z. Coon, J. Carlsen & J. M. Holub. J. Pept. Sci., 2017, 23,367-373. PubMed. PDF.
Targeting anti-apoptotic Bcl2 proteins with scyllatoxin-based BH3 domain mimetics. M. M. Harris, Z. Coon, N. Alqaeisoom, B. Swords & J. M. Holub. Org. Biomol. Chem., 2016, 14,440-446. PubMed. PDF.